Synthesis of 1,3,4‐Oxadiazole‐Based Aromatic and Heterocyclic/Phenylpyrazole Derivatives

A new series of 1,3,4‐oxadiazole‐based aromatic and heterocyclic/phenylpyrazole derivatives 6a–c , 7a–d , and 8 were synthesized via sequential 1,3‐dipolar cyclization, hydrazidation, benzoylation, dehydrative cyclization, and the Suzuki coupling reaction. Among the derivatives, compounds 7a and 7c with the corresponding 2‐thienyl and 2‐benzo[b]thienyl (Ar) at the phenyl group located at the N‐1 position of pyrazole showed a better conjugation range.      

Wideband subwavelength gratings for coupling between silicon-on-insulator waveguides and optical fibers

We propose and experimentally demonstrate a novel subwavelength grating coupler on silicon-on-insulator, for coupling to optical fibers with a wide optical bandwidth. Theoretical analysis and design optimization of the coupler are described. About 73?nm 1?dB bandwidth was experimentally demonstrated with -5.6 dB coupling efficiency. Better than -3.4 dB efficiency with 86?nm 1?dB bandwidth is predicted for these structures with optimized buried oxide thickness.     

Synthesis and biological evaluation of glycosylated psoralen derivatives

A novel route for the efficient synthesis of a target psoralen moiety, 4,4′-dimethylxanthotoxol, has been developed, which need only four steps using cheap pyrogallol as a starting material. Subsequently, a range of new glycosylated psoralen derivatives were synthesized in good yields with simple procedures and mild reaction conditions. The experiment of biological activity shows that some of the glycosylated psoralen derivatives have antiproliferative activities against human cancer cell lines. A strong photo-induced antiproliferative effects were found under UVA. All of the glycosylated psoralen derivatives exhibited antioxidant activities against the oxidation of DNA induced by Cu²⁺/glutathione (GSH). Further experiment also demonstrates that the introduction of sugar moieties in some glycosylated psoralen derivatives can improve their antioxidant activities significantly.     

Experimental verification of strong rotational dependence of fluorescence and predissociation yield in the b1Πu(v = 1) level of 14N2

New, rotationally resolved fluorescence-excitation spectra confirm coupled-channel Schro?dinger-equation predictions of strong rotational dependence of the fluorescence and predissociation yields in the b(v = 1) level of (14)N(2).     

Synthesis of Biomorphic ZrO2-CeO2 Nanostructures by Silkworm Silk Template

A simple and green technique has been developed to prepare hierarchical biomorphic ZrO₂-CeO₂, using silkworm silk as the template. Different from traditional immersion technics, the whole synthesis process depends more on the restriction or direction functions of the silkwormsilk template. The analytic results showed that ZrO₂-CeO₂ exhibited a well-crystallized hierarchically interwoven hollow fiber structure with 16-28 μm in diameter. The grain size of the sample calcined at 800 oC was about 14 nm. Consequently, the interwoven meshwork at three dimensions is formed due to the direction of biotemplate. The action mechanism is summarily discussed here. It may bring the biomorphic ZrO₂-CeO₂ nanomaterials with hierarchical interwoven structures to more applications, such as catalysts.     

NMR and FT-IR Investigation of Spinel LiMn2O4 Cathode Prepared by the Tartaric Acid Gel Process

The structure of the lithium manganese tartrate precursor and the synthesis mechanism of LiMn₂O₄ were investigated by FT-IR, NMR, TG/DSC, and XRD in this study. The results of FT-IR and ⁷Li and ¹³C NMR measurements revealed that lithium ions bond with carboxylic acid ligands and the O–H stretching modes of tartaric acid. Manganese ion bonds only with carboxylic acid. Lithium and manganese ions were trapped homogeneously on an atomic scale throughout the precursor. Such a structure eliminates the need for long-range diffusion during the formation of lithium manganese oxides. Therefore, spinel LiMn₂O₄ was synthesized at temperatures as low as 300°C. In this work, the electrochemical properties of Li/Li_xMn₂O₄ were studied. It is clear that the discharge curves exhibit two pseudo plateaus as the LiMn₂O₄ is fired to higher temperatures. The discharge capacity of LiMn₂O₄ increases from 84 to 117 mAh/g as the calcination temperature increases from 300 to 500°C. The LiMn₂O₄ powders calcined at low temperatures with a high specific surface area and an average valence of manganese exhibit a better cycle life.     

Synthesis of 4‐(5‐aryl‐1,3,4‐oxadiazol‐2‐yl)phenyl‐hydrazine derivatives from 3‐(4‐hydrazinocarbonyl‐phenyl)sydnones

The synthesis of potential fluorescent active 4‐(5‐aryl‐1,3,4‐oxadiazol‐2‐yl)phenylhydrazine derivatives was accomplished in three steps. The key step was the dehydration cyclization of 1,2‐diacylhydrazines to form the 1,3,4‐oxadiazole ring by use of acetic anhydride/perchloric acid mixture as the dehydrating agent. The sydnone moiety served as the masked hydrazines, which could be demasked by HCl for further application. © 2007 Wiley Periodicals, Inc. Heteroatom Chem 18:438–442, 2007; Published online in Wiley InterScience ( www.interscience.wiley.com ). DOI 10.1002/hc.20318     

生物力学与基因-献给周培源教授诞辰100周年

生物界包罗万象,其中有力的作用,所以有生物力学.自Galileo,Harvey, Boreli, Hooke, Euler,Young等创始以来,生物力学阐明了鸟飞鱼游,人体运动,血液循环,人工脏器等,对人世社会,有所贡献.生物力学的基础是质点力学,传统地用连续体力学的概念来简化.但近年做生物组织在应力的作用下改造的问题,引起了必须更改传统连续体力学的几个公理的问题.我们将仔细讨论这些公理,然后指出新公理存在的理由,是由于基因在细胞里的日常工作.基因不单主宰遗传,变异;并且忙着控制日常生活.不过,现在仅见其端倪.详细的情形,要等将来来阐发了.      

Nuclear stopping power in αα anddd collisions

Inelasticαα anddd collisions were studied at a centre-of-mass energy √S _NN=31.2 GeV per nucleon-nucleon collision, using the Split-Field Magnet (SFM) detector at the CERN ISR. In this paper we show the inclusive and semi-inclusive rapidity distributions of protons, compare them with predictions of the Lund model, and calculate the average rapidity loss for participant protons. From the negative particles we calculate the inelasticity of the interaction, the average energy per particle, and the degree of isotropy of the produced hadrons.     

The excitation energy spectrum of liquid He II based on theU-matrix theory

Summary In this paper, we apply theU-matrix theory to derive an explicit expression for the excitation energy spectrum of liquid⁴He. Using a model for the effective chemical potential for⁴He, we are able to produce an excitation spectrum which is very close to the observed one. The inverse of the effective mass,i.e. 1/m ^*, is obtained as a function of momentumk. The ratio between the effective mass and the mass of helium atom atk=2.0 ?⁻¹,i.e. near the roton depth, is found to bem ^*(k=2.0 ?⁻¹)/m _He=0.18298, while the ratio atk=1.0 ?⁻¹ ism ^*(k=1.0 ?⁻¹)/m _He=−0.17103. The theoretical result of the excitation spectrum is consistent with observational data.

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Riassunto In questo lavoro si applica la teoria della matriceU per dedurre un'espressione esplicita per lo spettro d'energia di eccitazione dell'⁴He liquido. Usando un modello per il potenziale chimico efficace per l'⁴He si è in grado di produrre uno spettro di eccitazione molto simile a quello osservato. L'inverso della massa efficace, cioè 1/m ^*, è ottenuto in funzione del momentok. Si trova che il rapporto tra massa efficace e la massa dell'atomo di elio ak=2.0 ?⁻¹, cioè vicino alla profondità del rotore, èm ^* (k=2.0 ?⁻¹)/m _He= =0.18298, mentre quello ak=1.0 ?⁻¹ èm ^* (k=1.0 ?⁻¹)/m _he=−0.17103. Il risultato teorico dello spettro di eccitazione è coerente con i dati sperimentali.

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Резюме В этой статье мы применяем теориюU-матрицы для вывода явного выражения для энергетического спектра возбуждений Зидкого⁴He. Используя модель для эффективного химического потенциала для⁴He, мы воспроизводим спектр возбуждений который оказывается очень близким к зкспериментально наблюдаемому. Вычисляется обратная величина эффективной массы, т.е. 1/m ^*, как функция импульсаk. Получено отношение эффективной массы к массе атома гелия приk=2.0 ?⁻¹, которое составляетm ^* (k=2.0 ?⁻¹)/m _He=0.18298, тогда как это отношение приk=1.0 ?⁻¹ равноm ^* (k=1.0 ?⁻¹)/m _He=−0.17103. Теоретический результат для спектра возбужений согласуется с имеющимися экспериментальными данными.